Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA558500

Invitrogen™ FGFR1OP2 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA558500
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA558500 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA558500 Supplier Invitrogen™ Supplier No. PA558500
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: ADAKALVERL RDHDDAAESL IEQTTALNKR VEAMKQYQEE IQELNEVARH RPRSTLVMGI QQENRQIREL QQENKELRTS LEEHQS Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

FGFR1OP2, also known as FGFR1 oncogene partner 2, is a gene that plays a crucial role in oncogenesis, particularly in myeloproliferative neoplasms. It is known to interact with the FGFR1 (Fibroblast Growth Factor Receptor 1) through chromosomal translocations that can lead to malignancies, such as the formation of the fusion protein FGFR1OP2-FGFR1 in KG-1a leukemic cells. FGFR1OP2 itself is a gene encoding a protein whose function is not entirely understood, but its association with FGFR1 highlights its potential role in oncogenic pathways. The FGFR1 component of the fusion is a receptor tyrosine kinase involved in various cellular processes like cell proliferation, migration, and differentiation. The disruption of these processes through abnormal expression or structural changes such as fusions can lead to uncontrolled cell growth and malignancies. FGFR1 is also frequently studied as a therapeutic target in cancer, given its importance in cellular signaling and cancer progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGFR1OP2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FGFR1OP2
Gene Accession No. Q9NVK5
Gene Alias 1500031J01Rik; FGFR1 oncogene partner 2; FGFR1 oncogene partner 2 homolog; FGFR1OP2; fibroblast growth factor receptor 1 oncogene partner 2; HSPC123; HSPC123-like; Wit3.0; Wit3.0_alpha; Wit3.0_beta; wound inducible transcript 3.0; wound inducible transcript 3.0 protein; wound-inducible transcript 3.0 protein
Gene Symbols FGFR1OP2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human FGFR1OP2. Recombinant protein control fragment (Product #RP-97727).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26127
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.