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FGFR2 Mouse anti-Human, Clone: OTI5C5, liquid, TrueMAB™
Mouse Monoclonal Antibody
Supplier: OriGene TA503137
Description
FGFR2 is a member of the fibroblast growth factor receptor family. It is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a central role in the regulation of cell proliferation, differentiation, migration, apoptosis, and embryonic development. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.Specifications
FGFR2 | |
Monoclonal | |
0.85 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
P21802 | |
FGFR2 | |
Full length human recombit protein of human FGFR2 produced in HEK293T cell. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG2b |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
OTI5C5 | |
Unconjugated | |
FGFR2 | |
BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25 | |
Mouse | |
Affinity Chromatography | |
RUO | |
2263 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
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