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FGFR2 Mouse anti-Human, Clone: OTI5F7, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA502829S

Catalog No. 50-167-3841


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Description

Description

FGFR2 is a member of the fibroblast growth factor receptor family. It is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a central role in the regulation of cell proliferation, differentiation, migration, apoptosis, and embryonic development. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Specifications

Specifications

FGFR2
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P21802
BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
Mouse
IgG2a
30 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2263
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI5F7
Unconjugated
FGFR2
Liquid
FGFR2
Full length human recombit protein of human FGFR2 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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