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Invitrogen™ FGFR2 Polyclonal Antibody

Catalog No. PIPA124764
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PIPA124764 50 μL
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Catalog No. PIPA124764 Supplier Invitrogen™ Supplier No. PA124764

Description

Rabbit Polyclonal Antibody

This antibody shows no cross reactivity with FGFR1 or FGFR3. The molecular weight is 110 kDa. Avoid freeze/thaw cycles.

FGFR2 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR family members differ from one another in their ligand affinities and tissue distribution. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGFR2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 15mM sodium azide; pH 7.4
Gene FGFR2
Gene Accession No. P21802, P21803
Gene Alias AU043015; AW556123; bacteria-expressed kinase; BBDS; BEK; BEK fibroblast growth factor receptor; BFR-1; CD332; CEK3; CFD1; ECT1; FGF Receptor; FGF Receptor 2; FGF-10; FGFR; FGFR2; FGFR-2; Fgfr7; Fgfr-7; fibroblast growth factor receptor 2; JWS; Keratinocyte growth factor receptor; KGFR; KGFRTr; KSAM; K-SAM; protein tyrosine kinase, receptor like 14; Soluble KGFR; svs; TK14; TK25
Gene Symbols FGFR2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 362-374 of the extracellular region of human FGFR-2 (Bek).
Purification Method Antigen affinity chromatography
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14183, 2263
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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