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FGFR2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980437
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Catalog No. Quantity
50-198-0437 100 μL
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Catalog No. 50-198-0437 Supplier Bioss Supplier No. BS0675R
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Description

Rabbit Polyclonal Antibody

FGFR2 is a member of the fibroblast growth factor receptor family. It is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a central role in the regulation of cell proliferation, differentiation, migration, apoptosis, and embryonic development. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Specifications

Antigen FGFR2
Applications Flow Cytometry, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene FGFR2
Gene Accession No. P21802
Gene Alias AU043015; AW556123; bacteria-expressed kinase; BBDS; BEK; BEK fibroblast growth factor receptor; BFR-1; CD332; CEK3; CFD1; Ect1; FGF Receptor 2; FGF-10; Fgfr2; FGFR-2; Fgfr7; Fgfr-7; Fibroblast growth factor receptor 2; JWS; Keratinocyte growth factor receptor; KGFR; KGFRTr; KSAM; K-sam; protein tyrosine kinase, receptor like 14; Soluble KGFR; svs; TK14; TK25
Gene Symbols FGFR2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human FGFR2 .
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2263
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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