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FGFR4/CD334 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980438
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100 μL
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Catalog No. Quantity
50-198-0438 100 μL
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Catalog No. 50-198-0438 Supplier Bioss Supplier No. BS0676R
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Description

Rabbit Polyclonal Antibody

FGFR4 (Fibroblast Growth Factor Receptor 4), is a member of the FGFR family of receptor tyrosine kinases. This family regulates a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR4 protein is a tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation, migration, and in the regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism, and phosphate homeostasis. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.

Specifications

Antigen FGFR4/CD334
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Fgfr4
Gene Accession No. P22455
Gene Alias CD334; CTLA-2-beta protein; FGF Receptor 4; FGFR4; Fgfr-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; Protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Gene Symbols Fgfr4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human FGFR4 .
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2264
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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