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FGFR4 Monoclonal Antibody (19H3), Invitrogen™

Catalog No. PIMA518084
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100 μL
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Catalog No. Quantity
PIMA518084 100 μL
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Catalog No. PIMA518084 Supplier Thermo Scientific Supplier No. MA518084

Description

Mouse Monoclonal Antibody

This target has a predicted molecular weight of 88 kDa. Actual Western blot results show a band at 105 kDa.

FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGFR4
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 19H3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene Fgfr4
Gene Accession No. P22455
Gene Alias CD334; CTLA-2-beta protein; FGF Receptor 4; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Gene Symbols Fgfr4
Host Species Mouse
Immunogen Cytoplasmic domain of human FGFR4 fused to maltose binding protein
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2264
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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