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Invitrogen™ FGFR4 Monoclonal Antibody (4FR6D3)
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Catalog No. PIMA528550
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100 μg
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Catalog No. Quantity
PIMA528550 100 μg
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Catalog No. PIMA528550 Supplier Invitrogen™ Supplier No. MA528550
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Description

Mouse Monoclonal Antibody

This antibody reacts with an extracellular epitope of CD334, the fibroblast growth factor receptor 4, which is an approximately 88 kDa receptor tyrosine kinase expressed in variety of tissues.

FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGFR4
Applications Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Clone 4FR6D3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene Fgfr4
Gene Accession No. P22455
Gene Alias CD334; CTLA-2-beta protein; FGF Receptor; FGF Receptor 4; FGFR; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Gene Symbols Fgfr4
Host Species Mouse
Immunogen full length human CD334- transfected NIH 3T3 cells.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2264
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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