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Invitrogen™ FGFR4 Monoclonal Antibody (7H1)
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Catalog No. PIMA515500
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100 μL
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Catalog No. Quantity
PIMA515500 100 μL
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Catalog No. PIMA515500 Supplier Invitrogen™ Supplier No. MA515500
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Description

Mouse Monoclonal Antibody

MA5-15500 targets FGFR4 in indirect ELISA, IF and WB applications and shows reactivity with Human samples. The MA5-15500 immunogen is purified recombinant extracellular fragment of human FGFR4 fused with hIgGFc tag expressed in HEK293 cell line. MA5-15500 detects FGFR4 which has a predicted molecular weight of approximately 87.9kDa.

FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGFR4
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 7H1
Concentration Conc. not determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene Fgfr4
Gene Accession No. P22455
Gene Alias CD334; CTLA-2-beta protein; FGF Receptor; FGF Receptor 4; FGFR; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Gene Symbols Fgfr4
Host Species Mouse
Immunogen Purified recombinant extracellular fragment of human FGFR4 fused with hIgGFc tag expressed in HEK293 cell line.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2264
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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