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Invitrogen™ FGFR4 Recombinant Rabbit Monoclonal Antibody (2C4E1)
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Catalog No. PIMA542915
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Quantity:
100 μL
Catalog No. Quantity
PIMA542915 100 μL
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Catalog No. PIMA542915

Supplier: Invitrogen™ MA542915

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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: HepG2, MCF7, Raji, Mouse lung. The target is usually found in the following locations: Cell membrane, Cytoplasm, Endoplasmic reticulum, Endosome, Secreted, Single-pass type I membrane protein. Immunogen sequence: SLLREGHRMD RPPHCPPELY GLMRECWHAA PSQRPTFKQL VEALDKVLLA VSEEYLDLRL TFGPYSPSGG DASSTCSSSD SVFSHDPLPL GSSSFPFGSG VQT.

FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGFR4
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 2C4E1
Concentration 3 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Fgfr4
Gene Accession No. P22455, Q03142
Gene Alias CD334; CTLA-2-beta protein; FGF Receptor; FGF Receptor 4; FGFR; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Gene Symbols Fgfr4
Host Species Rabbit
Immunogen Synthetic peptide
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14186, 2264
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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