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Invitrogen™ FGFR5 Polyclonal Antibody
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Catalog No. PIPA567015
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100 μL
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PIPA567015 100 μL
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Catalog No. PIPA567015 Supplier Invitrogen™ Supplier No. PA567015
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KATNGFGSLSV NYTLVVLDDI SPGKESLGPD SSSGGQEDPA SQQWARPRFT QPSKMRRRVI ARPVGSSVRL KCVAS Highest antigen sequence identity to the following orthologs - mouse 92%, rat 89%.

Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuro-ectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. A total of six members of the FGF receptor family have been identified and cloned. These include the Flg receptor or FGFR-1, the BEK receptor or FGFR-2, FGFR-3, FGFR-4, FGFR-5 and FGFR-6. These receptors usually contain an extracellular ligand-binding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. However, FGFR-5 lacks the cytoplasmic kinase domain. FGFR-5 is expressed in a broad range of tissues, including kidney, brain and lung, but it is preferentially expressed in pancreas, where it may play a role in the regulation of some pancreatic function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGFR5
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FGFRL1
Gene Accession No. Q8N441
Gene Alias alpha-L-iduronidase; FGF homologous factor receptor; FGF receptor-like protein 1; Fgfr5; FGFR-5; FGFR5beta; FGFR5gamma; Fgfrl1; FGFR-like protein; FHFR; fibroblast growth factor receptor 5; Fibroblast growth factor receptor-like 1; fibroblast growth factor receptor-like protein; UNQ480/PRO943
Gene Symbols FGFRL1
Host Species Rabbit
Immunogen Recombinant Human FGFR5. Recombinant protein control fragment (Product #RP-107656).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 53834
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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