Invitrogen™ FGL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543785

Catalog No. PIPA543785

Description

Peptide sequence: WTVLQARLDG STNFTRTWQD YKAGFGNLRR EFWLGNDKIH LLTKSKEMIL Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%.

Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role, such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively expressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.

Specifications

• Antigen: FGL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FGL2
• Gene Alias: AI385601; associated with MHV-3 induced prothrombinase activity; cytotoxic T-lymphocyte-specific protein; Fgl2; Fiblp; fibrinogen like 2; fibrinogen-like 2; fibrinogen-like protein 2; Fibroleukin; musfiblp; Prothrombinase; pT49; similar to Fibroleukin precursor (Fibrinogen-like protein 2) (pT49); T49
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10875
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q14314
• Gene Symbols: FGL2
• Immunogen: Synthetic peptide directed towards the middle region of human FGL2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG