Invitrogen™ FGL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554306

Catalog No. PIPA554306

Description

Immunogen sequence: RNGLLLPSTG APGEVGDNRV RELESEVNKL SSELKNAKEE INVLHGRLEK LNLVNMNNIE NYVDSKVANL TFVVNSLDGK CSKCP Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 68%.

Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role, such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively expressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.

Specifications

• Antigen: FGL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FGL2
• Gene Alias: AI385601; associated with MHV-3 induced prothrombinase activity; cytotoxic T-lymphocyte-specific protein; Fgl2; Fiblp; fibrinogen like 2; fibrinogen-like 2; fibrinogen-like protein 2; Fibroleukin; musfiblp; Prothrombinase; pT49; similar to Fibroleukin precursor (Fibrinogen-like protein 2) (pT49); T49
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10875
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q14314
• Gene Symbols: FGL2
• Immunogen: Recombinant protein corresponding to Human FGL2. Recombinant protein control fragment (Product #RP-92704).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG