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Invitrogen™ FGR Polyclonal Antibody
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Catalog No. PIPA579264
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100 μg
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Catalog No. Quantity
PIPA579264 100 μg
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Catalog No. PIPA579264 Supplier Invitrogen™ Supplier No. PA579264
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human SW579 whole cell.

FGR is a SRC-related kinase present in hematopoietic cells. FGR signals within multiple pathways including within the integrin pathway and downstream of chemokine and cytokine receptors. This protein contains N-terminal sites for myristylation and palmitoylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. It localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGR
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene FGR
Gene Accession No. P09769, P14234, Q6P6U0
Gene Alias c-fgr; c-fgr protooncogene; c-src2; c-src-2 proto-oncogene; EC 2.7.10.2; feline Gardner-Rasheed sarcoma viral oncogene; feline Gardner-Rasheed sarcoma viral oncogene homolog; FGR; FGR protein; FGR proto-oncogene, Src family tyrosine kinase; FLJ43153; Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; MGC75096; OTTHUMP00000003603; OTTHUMP00000003604; p55c-fgr; p55-c-fgr protein; p55-Fgr; p58c-Fgr; p58-Fgr; proto-oncogene c-Fgr; proto-oncogene tyrosine-protein kinase FGR; SRC2; Tyrosine-protein kinase Fgr; v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog
Gene Symbols FGR
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence of human FGR (ASLYEAMEQTWRLDPEERPTFEYLQ).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14191, 2268, 79113
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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