Invitrogen™ FHL2 Monoclonal Antibody (F4B2-B11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA140200

Catalog No. 01-676-550

Description

MA1-40200 detects FHL2 from human, mouse, and rat samples. MA1-40200 has been successfully used in immunohistochemistry (frozen), immunohistochemistry (paraffin), Western blot, and immunofluorescence applications. The MA1-40200 immunogen is human FHL2. MA1-40200 recognizes the N-terminal Zn-Finger motif, it does not crossreact in Western Blotting with the FHL1 and FHL3 proteins. MA1-40200 antibody is cross reactive with mouse and rat FHL2.

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified.

Specifications

• Antigen: FHL2
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide
• Gene Accession No.: O35115, O70433, Q14192
• Gene Symbols: Fhl2
• Immunogen: Bacterially-expressed mouse GST-FHL2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: F4B2-B11
• Conjugate: Unconjugated
• Gene: Fhl2
• Gene Alias: AAG11; aging-associated gene 11; down-regulated in rhabdomyosarcoma LIM protein; DRAL; Fhl2; FHL-2; four and a half LIM domains 2; four and a half LIM domains protein 2; LIM domain protein DRAL; OTTHUMP00000203164; OTTHUMP00000203168; OTTHUMP00000203169; skeletal muscle LIM-protein 3; SLIM 3; SLIM3; SLIM-3
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 14200, 2274, 63839
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

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