Invitrogen™ FHL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529906

Catalog No. PIPA529906

Description

Recommended positive controls: HeLa, mouse brain. Predicted reactivity: Mouse (93%), Rat (92%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified.

Specifications

• Antigen: FHL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fhl2
• Gene Alias: AAG11; aging-associated gene 11; down-regulated in rhabdomyosarcoma LIM protein; DRAL; Fhl2; FHL-2; four and a half LIM domains 2; four and a half LIM domains protein 2; LIM domain protein DRAL; OTTHUMP00000203164; OTTHUMP00000203168; OTTHUMP00000203169; skeletal muscle LIM-protein 3; SLIM 3; SLIM3; SLIM-3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14200, 2274
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.79 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O70433, Q14192
• Gene Symbols: Fhl2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 52 and 272 of Human FHL2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG