Invitrogen™ FHOD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555158

Catalog No. PIPA555158

Description

Immunogen sequence: QCGDILTNKR FMLDMLYAHN RKSPDDEEKG DGEAGRTQQE AEAVASLATR ISTLQANSQT QDESVRRVDV GCLDNRGSVK AFAEKFNSGD LGRGSISPDA EPNDKVPETA PVQPKTESDY IWDQLM Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 83%.

FHOD3 is a novel member of the formin homology family playing an important role in regulation of the actin cytoskeleton. It contains a DAD (diaphanous auto regulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. FHOD3 is a cytoplasmic protein where the main part of the protein localizes to actin fibers and the remaining part displays filamentous staining. A 1422 amino acid containing formin-related actin-organizing protein, FHOD3 may cause stress fiber formation together with cell elongation and may associate with nestin/NES-based interfilament (IF). Expression of FHOD3 is seen mainly in heart, kidney, and brain.

Specifications

• Antigen: FHOD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FHOD3
• Gene Alias: A930009H06Rik; FH1/FH2 domain-containing protein 3; Fhod3; Fhos2; Formactin2; Formactin-2; Formin homolog overexpressed in spleen 2; formin homology 2 domain containing 3; formin-family protein FHOS2; hFHOS2; KIAA1695; mFHOS2; mKIAA1695
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80206
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q2V2M9
• Gene Symbols: FHOD3
• Immunogen: Recombinant protein corresponding to Human FHOD3. Recombinant protein control fragment (Product #RP-88592).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG