Invitrogen™ Fibrillarin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589262

Catalog No. PIPA589262

Description

Immunogen sequence: RGKEDALVTK NLVPGESVYG EKRVSISEGD DKIEYRAWNP FRSKLAAAIL GGVDQIHIKP GAKVLYLGAA SGTTVSHVSD IVGPDGLVYA VEFSHRSGRD LINLAKKRTN IIPVIEDARH PHKYRMLIAM VDVIFADVAQ PDQTRIVALN AHTFLRNGGH FVISIKANCI DSTASAEAVF ASEVKKMQQE NMKPQEQLTL EPYERDHAVV VGVYRPPPKV KN; Positive Samples: HeLa, A375, U-2OS, COS-1, COS-7, PC-12, Mouse brain; Cellular Location: Nucleus, nucleolus.

Nop1p / Fibrillarin was originally identified as a nucleolar protein of bakers yeast, Saccharomyces cerevisiae (accession P15646). The Nop1p protein is essential for yeast viability and is localized in the nucleoli. The human homologue of Nop1p is fibrillarin (accession P22087) a component of the nucleolar small nuclear ribonucleoprotein (snRNP) particle. The human fibrillarin gene is located on chromosome 19 (19q13. 1).

Specifications

• Antigen: Fibrillarin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: fbl
• Gene Alias: 34 kDa nucleolar scleroderma antigen; 34-kD nucleolar scleroderma antigen; AL022665; AT20009p; CELE_T01C3.7; CG5725; CG5725-PA; CG5725-PB; CG5725-PC; CG5725-PD; CG5725-PE; CG5725-PF; CG5725-PG; Dmel\CG5725; Dmel_CG5725; dPANK; dPANK/Fbl; Fbl; fbl-PA; fbl-PB; fbl-PC; fbl-PD; fbl-PE; fbl-PF; fbl-PG; FIB; FIB1; fib-1; fibrillarin; FLRN; fumble; histone-glutamine methyltransferase; LD24618p; LP11571p; nucleolar protein 1; PANK; pantothenate kinase; RNA, U3 small nucleolar interacting protein 1; RNU3IP1; rRNA 2'-O-methyltransferase fibrillarin; T01C3.7
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14113, 2091, 292747
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 2.68 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P22087, P22509, P35550
• Gene Symbols: fbl
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-321 of human Fibrillarin/U3 RNP (NP_0014272).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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