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Invitrogen™ Fibrillin 1 Monoclonal Antibody (CL0225)
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Catalog No. PIMA534972
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PIMA534972 100 μL
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Catalog No. PIMA534972 Supplier Invitrogen™ Supplier No. MA534972
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Description

Mouse Monoclonal Antibody

Immunogen sequence: DVRPGYCYTA LTNGRCSNQL PQSITKMQCC CDAGRCWSPG VTVAPEMCPI RATEDFNKLC SVPMVIPGRP EYPPPPLGPI PPVLPVPPGF PPGPQIPVPR PPVEYLYPSR EPPRVLPVNV TDYCQLVRYL CQNGRCIPTP GSCRCEC Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 89%.

Fibrillin 1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape with mosaic composition of different types of extracellular modules. Most of the fibrillin molecule is contributed by 47 epidermal growth factor-like (EGF-like) repeats; 43 of them have a consensus sequence for calcium binding (cb). Other modules including 8-cysteine motifs (seven), hybrid motifs (two), and unique domains (three) are interspersed throughout the molecule[3-7]. Fibrillin 1 contains a proline-rich region close to the N-terminus that is replaced by a glycine-rich region in Fibrillin 2. The fibrillins are found throughout the connective tissue as integral components of extended fibrils.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Fibrillin 1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CL0225
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FBN1
Gene Accession No. P35555
Gene Alias ACMICD; AI536462; Asprosin; B430209H23; ECTOL1; FBN; Fbn1; Fbn-1; Fib-1; fibrillin 1; fibrillin 15; fibrillin-1; GPHYSD2; MASS; MFLS; MFS1; MP340; OCTD; putative; SGS; SSKS; tight skin; Tsk; WMS; WMS2
Gene Symbols FBN1
Host Species Mouse
Immunogen Recombinant protein fragment of Human FBN1 (Product #RP-90822)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2200
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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