Invitrogen™ Fibrinogen Beta Chain Monoclonal Antibody (2#)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA541586

Catalog No. PIMA541586

Description

Fibrinogen Beta Chain Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Specifications

• Antigen: Fibrinogen Beta Chain
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P02675
• Gene Symbols: Fgb
• Immunogen: Recombinant protein Fibrinogen Beta Chain. The antigen corresponds to amino acid range 45-491 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 2#
• Conjugate: Unconjugated
• Gene: Fgb
• Gene Alias: 2510049G14Rik; Ab1-181; Ab1-216; Ac1-581; B beta polypeptide; beta-fibrinogen; epididymis secretory sperm binding protein Li 78p; Fgb; fibrinogen; Fibrinogen beta chain; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; Fibrinopeptide B; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC104327; MGC120405
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 2244
• Content And Storage: -20°C
• Form: Liquid