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Invitrogen™ Fibrinogen gamma Monoclonal Antibody (5H9)
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Catalog No. PIMA549169
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100 μg
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PIMA549169 100 μg
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Catalog No. PIMA549169 Supplier Invitrogen™ Supplier No. MA549169
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Description

Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Immunogen sequence is different from the related mouse sequence by two amino acids, and from the related rat sequence by five amino acids. Positive Control - WB: human HepG2 whole cell, human HepG2 whole cell. ICC/IF: HEP3B cell. Flow: HepG2 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Fibrinogen gamma
Applications Western Blot, Immunocytochemistry, Western Blot
Classification Monoclonal
Clone 5H9
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene Fgg
Gene Accession No. P02679
Gene Alias 3010002H13Rik; AI256424; FGG; fibg; fibrinogen; fibrinogen gamma chain; Fibrinogen gamma-B chain; fibrinogen gamma-chain; fibrinogen, gamma polypeptide; gamma'; gamma-fibrinogen; PRO2061; testicular tissue protein Li 70; Unknown (protein for MGC:127951)
Gene Symbols Fgg
Host Species Mouse
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human FGG (133-163aa IRYLQEIYNSNNQKIVNLKEKVAQLEAQCQE).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2266
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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