Invitrogen™ Fibrinogen gamma Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595397

Catalog No. PIPA595397

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human HepG2 whole cell, human hepatocellular carcinoma tumor tissue (HCCT), human hepatocellular carcinoma paracancerous tissue (HCCP), rat liver tissue, mouse liver tissue. IHC: human liver cancer tissue. Flow: SiHa cell, A549 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Specifications

• Antigen: Fibrinogen gamma
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fgg
• Gene Alias: 3010002H13Rik; AI256424; FGG; fibg; fibrinogen; fibrinogen gamma chain; Fibrinogen gamma-B chain; fibrinogen gamma-chain; fibrinogen, gamma polypeptide; gamma'; gamma-fibrinogen; PRO2061; testicular tissue protein Li 70; Unknown (protein for MGC:127951)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2266, 24367, 99571
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P02679, P02680, Q8VCM7
• Gene Symbols: Fgg
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human FGG (133-163aa IRYLQEIYNSNNQKIVNLKEKVAQLEAQCQE).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG