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Invitrogen™ Fibrinogen Polyclonal Antibody
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Catalog No. PIPA5115224
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100 μL
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PIPA5115224 100 μL
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Catalog No. PIPA5115224 Supplier Invitrogen™ Supplier No. PA5115224
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total FGA.

Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Fibrinogen
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene FGG
Gene Accession No. P02671, P02675, P02679, P02680, P06399, P14480
Gene Alias 2510049G14Rik; 3010002H13Rik; A-alpha fibrinogen; Ab1-181; Ab1-216; Ac1-581; Ac1873; AI256424; carboxy-terminal region; ENSMUSG00000059807; epididymis secretory sperm binding protein Li 78p; Fba5e; Fga; Fgb; Fgg; Fib; Fib2; fibg; fibrinogen; fibrinogen A-alpha chain; fibrinogen A-alpha-chain; fibrinogen alpha chain; fibrinogen alpha-E subunit; fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen gamma polypeptide; fibrinogen gamma-B chain; fibrinogen gamma-chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; Gamma'; gamma-fibrinogen; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC119422; MGC119423; MGC119425; PRO2061; testicular tissue protein Li 70; Unknown (protein for MGC:127951)
Gene Symbols FGA, FGB, FGG
Host Species Rabbit
Immunogen A synthesized peptide derived from human FGA(Accession P02671), corresponding to amino acid residues W807-R857.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2243, 2244, 2266, 24366, 24367, 361969
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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