Fibrinogen Polyclonal Antibody, Biotin, Rockland™

Catalog No.	Quantity
50-199-0431	100 μg
50-199-0432	25 μL

Catalog No. 50-199-0431 Supplier Rockland Immunochemicals Supplier No. 2001062400100

Description

Goat Polyclonal Antibody

Store vial at 4°C prior to restoration. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Anti-Fibrinogen antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Biotin, anti-Goat Serum as well as purified and partially purified Fibrinogen [Human Plasma]. Cross reactivity against Fibrinogen from other sources is unknown.

Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.

Specifications

• Antigen: Fibrinogen
• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Biotin
• Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
• Gene: FGB
• Gene Accession No.: P02671, P02675, P02679
• Gene Alias: 2510049G14Rik; 3010002H13Rik; Ab1-181; Ab1-216; Ac1-581; Ac1873; AI256424; ENSMUSG00000059807; epididymis secretory sperm binding protein Li 78p; Fba5e; FGA; Fgb; FGG; Fib; Fib2; Fibrinogen alpha chain; Fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen gamma-chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; gamma-fibrinogen; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC119422; MGC119423; MGC119425; PRO2061; testicular tissue protein Li 70
• Gene Symbols: FGA, FGB, FGG
• Host Species: Goat
• Immunogen: Fibrinogen [Human Plasma]
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2243, 2244, 2266
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Lyophilized