Invitrogen™ Fibrinogen Recombinant Superclonal™ Antibody (12 HCLC)

Rabbit Recombinant Superclonal Antibody

Supplier:  Invitrogen™ 710386

Catalog No. PI710386

Description

This antibody is predicted to react with non-human primate based on sequence homology. Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called Recombinant polyclonal antibody, this product is now rebranded as Recombinant Superclonal™ antibody. The physical product and the performance remain unchanged.

Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.

Specifications

• Antigen: Fibrinogen
• Classification: Recombinant Superclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: P02671, P02675, P02679
• Gene Symbols: FGA, FGB, FGG
• Immunogen: Immunogens consist of peptides corresponding to aa 195-204 and aa 614-628 of human fibrinogen.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 12 HCLC
• Conjugate: Unconjugated
• Gene: FGG
• Gene Alias: 2510049G14Rik; 3010002H13Rik; A-alpha fibrinogen; Ab1-181; Ab1-216; Ac1-581; Ac1873; AI256424; carboxy-terminal region; ENSMUSG00000059807; epididymis secretory sperm binding protein Li 78p; Fba5e; Fga; Fgb; Fgg; Fib; Fib2; fibg; fibrinogen; fibrinogen A-alpha chain; fibrinogen A-alpha-chain; fibrinogen alpha chain; fibrinogen alpha-E subunit; fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen gamma polypeptide; fibrinogen gamma-B chain; fibrinogen gamma-chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; Gamma'; gamma-fibrinogen; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC119422; MGC119423; MGC119425; PRO2061; testicular tissue protein Li 70; Unknown (protein for MGC:127951)
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2243, 2244, 2266
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid