Invitrogen™ Fibromodulin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527784

Catalog No. PIPA527784

Description

Recommended positive controls: HeLa, HepG2. Predicted reactivity: Mouse (91%), Rat (90%), Rhesus Monkey (98%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.

Specifications

• Antigen: Fibromodulin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FMOD
• Gene Alias: AI131919; AU041740; Collagen-binding 59 kDa protein; fibromodulin; FM; FMOD; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin; SLRR2E
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2331
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q06828
• Gene Symbols: FMOD
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Fibromodulin. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG