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  6. Fibulin-1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech 

Fibulin-1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501732883 Shop All Proteintech Group Inc Products
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50-173-2883 150 μL
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Catalog No. 50-173-2883 Supplier Proteintech Group Inc Supplier No. 204251AP150UL
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Description

Rabbit Polyclonal Antibody

Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes and blood. Fibulin-1 self associates as well as binds to calcium, fibronectin, laminin, nidogen and fibrinogen. These interactions, individually or in combination, may account for the observed association of Fibulin-1 with basement membranes, connective tissue, elastic fibers and fibrin clots. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. Other studies point to the inhibition of cancer cell motility with increasing exposure to Fibulin-1. The exact function of Fibulin-1 in the cell is unknown.

Specifications

Antigen Fibulin-1
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.24 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene FBLN1
Gene Accession No. P23142, Q08879
Gene Alias FBLN, FBLN1, FIBL 1, Fibulin-1
Gene Symbols Fbln1
Host Species Rabbit
Immunogen Fibulin-1 Fusion Protein Ag14249
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14114, 2192, 315191
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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