Fibulin 1 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0523	100 μL

Catalog No. 50-198-0523 Supplier Bioss Supplier No. BS0809R

Description

Rabbit Polyclonal Antibody

Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes and blood. Fibulin-1 self associates as well as binds to calcium, fibronectin, laminin, nidogen and fibrinogen. These interactions, individually or in combination, may account for the observed association of Fibulin-1 with basement membranes, connective tissue, elastic fibers and fibrin clots. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. Other studies point to the inhibition of cancer cell motility with increasing exposure to Fibulin-1. The exact function of Fibulin-1 in the cell is unknown.

Specifications

• Antigen: Fibulin 1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Fbln1
• Gene Accession No.: P23142
• Gene Alias: Basement-membrane protein 90; BM-90; BM-90/fibulin extracellular matrix glyroprotein; BOS_6217; extracellular matrix; extracellular matrix and blood protein; FBLN; FBLN1; fbln1c; fbln1d; FIBL1; FIBL-1; fibulin 1; fibulin 1C; fibulin 1D; Fibulin1; Fibulin-1; fibulin-1 C varible region; fibulin-1 D; LOW QUALITY PROTEIN: fibulin-1; PP213; wu:fc52c06
• Gene Symbols: Fbln1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Fibulin 1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2192
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG