Invitrogen™ Ficolin 3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542017

Catalog No. PIPA542017

Description

Peptide sequence: LEASKVVLLP SCPGAPGSPG EKGAPGPQGP PGPPGKMGPK GEPGDPVNLL Sequence homology: Cow: 91%; Dog: 79%; Guinea Pig: 77%; Horse: 100%; Human: 100%; Mouse: 91%; Pig: 91%; Rabbit: 79%; Rat: 100%; Zebrafish: 92%.

H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.

Specifications

• Antigen: Ficolin 3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FCN3
• Gene Alias: Collagen/fibrinogen domain-containing lectin 3 p35; Collagen/fibrinogen domain-containing protein 3; FCN3; FCNH; ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); ficolin 3; ficolin-3; HAKA1; Hakata antigen; LOW QUALITY PROTEIN: ficolin-3; MGC22543
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8547
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O75636
• Gene Symbols: FCN3
• Immunogen: Synthetic peptide directed towards the N-terminal of human FCN3 (aa 35-84).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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