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Invitrogen™ FIG4 Polyclonal Antibody
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Catalog No. PIPA5120353
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Catalog No. PIPA5120353 Supplier Invitrogen™ Supplier No. PA5120353
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Rabbit Polyclonal Antibody

Positive test controls include: U-251MG, HT-29, Jukat, HeLa, Mouse liver, Mouse spleen. The target is usually found in the following locations: Endosome membrane. Immunogen sequence: WELPTDFYLH HKNTMRLLPT RRSYTYWWTP EVIKHLPLPY DEVICAVNLK KLIVKKFHKY EEEIDIHNEF FRPYELSSFD DTFCLAMTSS ARDFMPKTVG IDPSPFTVRK PDETGKSVLG NKSNREEAVL QRKTAASAPP PPSEEAVSSS SEDDSGTDRE EEGSVSQRST PVKMTDAGDS AKVTENVVQP MKELYGINLS DGLSEEDFSI YSRFVQLGQS QHKQDKNSQQ PCSRCSDGVI KLTPISAFSQ DNIYEVQPPR VDRKSTEIFQ AHIQASQGIM QPLGKEDSSM YREYIRNRYL.

The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FIG4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene FIG4
Gene Accession No. Q91WF7, Q92562
Gene Alias A530089I17Rik; AI326867; ALS11; BTOP; CMT4J; dJ249I4.1; FIG4; FIG4 homolog (S. cerevisiae); FIG4 homolog, SAC domain containing lipid phosphatase; FIG4 homolog, SAC1 domain containing lipid phosphatase; FIG4 homolog, SAC1 lipid phosphatase domain containing; FIG4 phosphoinositide 5-phosphatase; KIAA0274; Phosphatidylinositol 3,5-bisphosphate 5-phosphatase; polyphosphoinositide phosphatase; RGD1311375; RP1-249I4.1; Sac domain-containing inositol phosphatase 3; SAC domain-containing protein 3; Sac3; YVS
Gene Symbols FIG4
Host Species Rabbit
Immunogen Recombinant Protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 103199, 9896
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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