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FIG4 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA522083
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PIPA522083 100 μL
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Catalog No. PIPA522083 Supplier Thermo Scientific Supplier No. PA522083
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa , HCT116. Predicted reactivity: Mouse (95%), Rat (93%), Dog (98%), Pig (97%), Chicken (90%), Rhesus Monkey (99%), Chimpanzee (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FIG4
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene FIG4
Gene Accession No. Q92562
Gene Alias A530089I17Rik; AI326867; ALS11; BTOP; CMT4J; dJ249I4.1; FIG4; FIG4 homolog (S. cerevisiae); FIG4 homolog, SAC domain containing lipid phosphatase; FIG4 homolog, SAC1 domain containing lipid phosphatase; FIG4 homolog, SAC1 lipid phosphatase domain containing; FIG4 phosphoinositide 5-phosphatase; KIAA0274; Phosphatidylinositol 3,5-bisphosphate 5-phosphatase; polyphosphoinositide phosphatase; RGD1311375; RP1-249I4.1; Sac domain-containing inositol phosphatase 3; SAC domain-containing protein 3; Sac3; YVS
Gene Symbols FIG4
Host Species Rabbit
Immunogen Recombinant fragment corresponding to a region within amino acids 135 and 430 of FIG4 (Uniprot ID#Q92562)
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9896
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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