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Invitrogen™ Filaggrin 2 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555951

Catalog No. PIPA555951


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Description

Description

Immunogen sequence: CGYSNSSGCG RPQNASSSCQ SHRFGGQGNQ FSYIQSGCQS GIKGGQGHGC VSGGQPSGCG QPESNPCSQS YSQRGYGARE NGQPQNCGGQ WRTGSSQSSC CG Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 35%.

The FLG2 protein is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. FLG2 is also required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Filaggrin 2
Polyclonal
Unconjugated
FLG2
filaggrin family member 2; filaggrin-2; FLG2; FLG-2; Ifapsoriasin; IFPS; intermediate filament-associated and psoriasis susceptibility protein; intermediate filament-associated and psoriasis-susceptibility protein
Rabbit
Antigen Affinity Chromatography
RUO
388698
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin)
0.08 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q5D862
FLG2
Recombinant protein corresponding to Human Filaggrin 2. Recombinant protein control fragment (Product #RP-94294).
100 μL
Primary
Human
Antibody
IgG
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