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Invitrogen™ Filamin A alpha-1 Polyclonal Antibody
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Catalog No. PIPA529062
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100 μL
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PIPA529062 100 μL
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Catalog No. PIPA529062 Supplier Invitrogen™ Supplier No. PA529062
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431. Predicted reactivity: Mouse (98%), Rat (96%), Rabbit (98%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Filamin A alpha-1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene FLNA
Gene Accession No. P21333
Gene Alias ABP-280; ABPX; actin binding protein 280; Actin-binding protein 280; alpha filamin; alpha-filamin; CSBS; CVD1; Endothelial actin-binding protein; filamin A; filamin A, alpha; filamin-1; Filamin-A; FLN; FLN1; FLNA; FLN-A; FMD; MNS; NHBP; Non-muscle filamin; OPD; OPD1; OPD2; XLVD; XMVD
Gene Symbols FLNA
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human Filamin A. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2316
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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