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Invitrogen™ Filamin B Monoclonal Antibody (11E2D2)
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Catalog No. PIMA549226
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100 μg
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Catalog No. Quantity
PIMA549226 100 μg
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Catalog No. PIMA549226 Supplier Invitrogen™ Supplier No. MA549226
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Description

Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human A549 whole cell. IHC: human lung cancer tissue, human lymph node of rectal cancer tissue, human metaplasia of squamous cells of the renal pelvis tissue, human spleen tissue. ICC/IF: Hela cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Filamin B
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 11E2D2
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene FLNB
Gene Accession No. O75369
Gene Alias ABP-278; ABP-280; ABP-280 homolog; ABP-280-like protein; actin binding protein 278; actin-binding-like protein; AL024016; AOI; beta-filamin; Fh1; filamin B; filamin B, beta; filamin homolog 1; filamin, beta; filamin-3; FilaminB; Filamin-B; FLN1L; FLN3; FLNB; FLN-B; Larsen syndrome 1 (autosomal dominant); LRS1; SCT; TABP; TAP; thyroid autoantigen; Truncated ABP; Truncated actin-binding protein
Gene Symbols FLNB
Host Species Mouse
Immunogen E.coli-derived human Filamin B/FLNB recombinant protein (Position: Q397-D701).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2317
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG1
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