Invitrogen™ Filamin B Monoclonal Antibody (GT1282)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531544

Catalog No. PIMA531544

Description

Keep as concentrated solution. Predicted reactivity: Mouse (98%), Rat (98%), Chicken (97%), Bovine (99%). Positive Control: 293T, A431, HeLa, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.

Specifications

• Antigen: Filamin B
• Classification: Monoclonal
• Concentration: 1.83 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O75369
• Gene Symbols: FLNB
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Filamin B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: GT1282
• Conjugate: Unconjugated
• Gene: FLNB
• Gene Alias: ABP-278; ABP-280; ABP-280 homolog; ABP-280-like protein; actin binding protein 278; actin-binding-like protein; AL024016; AOI; beta-filamin; Fh1; filamin B; filamin B, beta; filamin homolog 1; filamin, beta; filamin-3; FilaminB; Filamin-B; FLN1L; FLN3; FLNB; FLN-B; Larsen syndrome 1 (autosomal dominant); LRS1; SCT; TABP; TAP; thyroid autoantigen; Truncated ABP; Truncated actin-binding protein
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 2317, 306204
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid