Invitrogen™ Filamin B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596132

Catalog No. PIPA596132

Description

Immunogen sequence: PDGTEAEADV IENEDGTYDI FYTAAKPGTY VIYVRFGGVD IPNSPFTVMA TDGEVTAVEE APVNACPPGF RPWVTEEAYV PVSDMNGLGF KPFDLVIPFA; Positive Samples: HeLa, NIH/3T3, A-431, Mouse liver, Mouse kidney, Mouse uterus, Rat lung; Cellular Location: Cytoplasm, Z line, cell cortex, cytoskeleton, myofibril, sarcomere.

FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.

Specifications

• Antigen: Filamin B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FLNB
• Gene Alias: ABP-278; ABP-280; ABP-280 homolog; ABP-280-like protein; actin binding protein 278; actin-binding-like protein; AL024016; AOI; beta-filamin; Fh1; filamin B; filamin B, beta; filamin homolog 1; filamin, beta; filamin-3; FilaminB; Filamin-B; FLN1L; FLN3; FLNB; FLN-B; Larsen syndrome 1 (autosomal dominant); LRS1; SCT; TABP; TAP; thyroid autoantigen; Truncated ABP; Truncated actin-binding protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2317, 286940, 306204
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.12 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O75369, Q80X90
• Gene Symbols: FLNB
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1686-1785 of human FLNB (NP_0011577891).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov