Invitrogen™ Filensin Monoclonal Antibody (FIL-7B10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA125031

Catalog No. PIMA125031

Description

Recommended positive controls: bovine lens. MA1-25031 will not react with mouse, rat, or chicken. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Filensin
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 15mM sodium azide
• Gene Accession No.: Q06002, Q12934
• Gene Symbols: BFSP1
• Immunogen: Human and bovine lens filament enriched fraction (plasma membrane cytoskeleton complex).
• Regulatory Status: RUO
• Gene ID (Entrez): 101121536, 281644, 631
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Western Blot
• Clone: FIL-7B10
• Conjugate: Unconjugated
• Gene: BFSP1
• Gene Alias: Beaded filament structural protein 1; beaded filament structural protein 1, filensin; BFSP1; CP115; CP94; CTRCT33; cytoskeletal protein, 115 KD; filensin; Lens fiber cell beaded-filament structural protein CP 115; lens intermediate filament-like heavy; LIFL-H; LOW QUALITY PROTEIN: filensin; RP4-531H16.2
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Bovine, Sheep
• Product Type: Antibody
• Isotype: IgG1