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Invitrogen™ Filensin Monoclonal Antibody (FIL-7B10)
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Catalog No. PIMA125031
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100 μL
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Catalog No. Quantity
PIMA125031 100 μL
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Catalog No. PIMA125031 Supplier Invitrogen™ Supplier No. MA125031
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Description

Mouse Monoclonal Antibody

Recommended positive controls: bovine lens. MA1-25031 will not react with mouse, rat, or chicken. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene.
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Specifications

Antigen Filensin
Applications Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Clone FIL-7B10
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 15mM sodium azide
Gene BFSP1
Gene Accession No. Q06002, Q12934
Gene Alias Beaded filament structural protein 1; beaded filament structural protein 1, filensin; BFSP1; CP115; CP94; CTRCT33; cytoskeletal protein, 115 KD; filensin; Lens fiber cell beaded-filament structural protein CP 115; lens intermediate filament-like heavy; LIFL-H; LOW QUALITY PROTEIN: filensin; RP4-531H16.2
Gene Symbols BFSP1
Host Species Mouse
Immunogen Human and bovine lens filament enriched fraction (plasma membrane-cytoskeleton complex).
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 101121536, 281644, 631
Target Species Human, Bovine, Sheep
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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