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Invitrogen™ Filensin Polyclonal Antibody
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Catalog No. PIPA559279
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100 μL
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PIPA559279 100 μL
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Catalog No. PIPA559279 Supplier Invitrogen™ Supplier No. PA559279
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Rabbit Polyclonal Antibody

Immunogen sequence: SAHECHDDEI QLYNEQIETL RKEIEETERV LEKSSYDCRQ LAVAQQTLKN ELDRYHRIIE IEGNRLTSAF IETPIPLFTQ SHGVSLSTGS GGKD Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 82%.

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Filensin
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BFSP1
Gene Accession No. Q12934
Gene Alias Beaded filament structural protein 1; beaded filament structural protein 1, filensin; BFSP1; CP115; CP94; CTRCT33; cytoskeletal protein, 115 KD; filensin; Lens fiber cell beaded-filament structural protein CP 115; lens intermediate filament-like heavy; LIFL-H; LOW QUALITY PROTEIN: filensin; RP4-531H16.2
Gene Symbols BFSP1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Filensin. Recombinant protein control fragment (Product #RP-99408).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 631
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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