Invitrogen™ Filensin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559279

Catalog No. PIPA559279

Description

Immunogen sequence: SAHECHDDEI QLYNEQIETL RKEIEETERV LEKSSYDCRQ LAVAQQTLKN ELDRYHRIIE IEGNRLTSAF IETPIPLFTQ SHGVSLSTGS GGKD Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 82%.

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Filensin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BFSP1
• Gene Alias: Beaded filament structural protein 1; beaded filament structural protein 1, filensin; BFSP1; CP115; CP94; CTRCT33; cytoskeletal protein, 115 KD; filensin; Lens fiber cell beaded-filament structural protein CP 115; lens intermediate filament-like heavy; LIFL-H; LOW QUALITY PROTEIN: filensin; RP4-531H16.2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 631
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q12934
• Gene Symbols: BFSP1
• Immunogen: Recombinant protein corresponding to Human Filensin. Recombinant protein control fragment (Product #RP-99408).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG