FIP1L1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA557963

Catalog No. PIPA557963

Description

Immunogen sequence: KANSSVGKWQ DRYGRAESPD LRRLPGAIDV IGQTITISRV EGRRRANENS NIQVLSERSA TEVDNNFSKP PPFFPPGAPP T Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. It binds to U-rich RNA sequence elements surrounding the poly(A) site. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex.

Specifications

• Antigen: FIP1L1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FIP1L1
• Gene Alias: 1300019H17Rik; DKFZp586K0717; Factor interacting with PAP; factor interacting with PAPOLA and CPSF1; FIP1; FIP1 like 1; FIP1 like 1 (S. cerevisiae); FIP1 like 1b (S. cerevisiae); FIP1L1; FIP1L1 cleavage and polyadenylation specific factor subunit; fip1l1b; FIP1-like 1 protein; FLJ33619; hFip1; Pre-mRNA 3'-end-processing factor FIP1; pre-mRNA 3'-end-processing factor FIP1; LOW QUALITY PROTEIN: pre-mRNA 3'-end-processing factor FIP1; rearranged in hypereosinophilia; RHE; Rje; wu:fd36f11; zgc:103421
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81608
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6UN15
• Gene Symbols: FIP1L1
• Immunogen: Recombinant protein corresponding to Human FIP1L1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov

Research Use Only