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Tocris Bioscience™ FITM
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Catalog No. 685910
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Catalog No. Quantity
68-591-0 10 mg
68-595-0 50 mg
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Catalog No. 68-591-0 Supplier Tocris Bioscience™ Supplier No. 6859/10
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Description

Potent and selective negative allosteric modulator of mGlu1 receptors

FITM is a potent and selective negative allosteric modulator of mGlu1 receptors (IC50 = 5.1 nM). Displays >1300-fold selectivity for mGlu1 over other metabotropic glutamate receptors (IC50 values are 7 μM and >10 μM for mGlu5 and mGlu2 or mGlu8, respectively). Antagonizes methamphetamine-induced locomotion in mice.

Specifications

Quantity 10 mg
Molecular Formula C18H18FN5OS
Formula Weight 371.43
Product Type Negative Allosteric Modulator
Purity 98%
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