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  5. Tocris Bioscience™ FITM

Tocris Bioscience™ FITM
GREENER_CHOICE

Catalog No. 685910
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective negative allosteric modulator of mGlu1 receptors

FITM is a potent and selective negative allosteric modulator of mGlu1 receptors (IC50 = 5.1 nM). Displays >1300-fold selectivity for mGlu1 over other metabotropic glutamate receptors (IC50 values are 7 μM and >10 μM for mGlu5 and mGlu2 or mGlu8, respectively). Antagonizes methamphetamine-induced locomotion in mice.

Specifications

Quantity 10 mg
Molecular Formula C18H18FN5OS
Formula Weight 371.43
Product Type Negative Allosteric Modulator
Purity 98%
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