FK506 Antibody (FK1), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NB10062571

Catalog No. NB10062571

Description

FK506 Monoclonal specifically detects FK506 in Non-species specific samples. It is validated for ELISA.

Specifications

• Antigen: FK506
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Dilution: ELISA 1:100-1:2000
• Immunogen: FK-506-BSA conjugate
• Quantity: 0.1 mg
• Primary or Secondary: Primary
• Target Species: Non-species specific
• Form: Purified

• Applications: ELISA
• Clone: FK1
• Conjugate: Unconjugated
• Host Species: Mouse
• Purification Method: IgM purified
• Regulatory Status: RUO
• Test Specificity: NB100-62571 detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgM

For Research Use Only