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Invitrogen™ FKBP12 Polyclonal Antibody
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Catalog No. PIPA580636
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100 μL
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PIPA580636 100 μL
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Catalog No. PIPA580636 Supplier Invitrogen™ Supplier No. PA580636
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Description

Rabbit Polyclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human FKBP1A/FKBP12.

FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FKBP12
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene FKBP1A
Gene Accession No. P62942
Gene Alias 12 kDa FK506-binding protein; 12 kDa FKBP; calstabin 1; calstabin-1; EC 5.2.1.8; FK506 binding protein 1a; FK506 binding protein 1A, 12kDa; FK506 binding protein 2 (13 kDa); FK506 binding protein12; FK506-binding protein 1; FK506-binding protein 1 (12kD); FK506-binding protein 12; FK506-binding protein 1a; FK506-binding protein 1A (12kD); FK506-binding protein, T-cell, 12-kD; Fkbp; FKBP1; FKBP12; FKBP-12; FKBP12-Exip3; Fkbp1a; FKBP-1A; Fkbp2; Immunophilin FKBP12; peptidyl-prolyl cis-trans isomerase FKBP1A; PKC12; PKCI2; PPIASE; PPIase FKBP1A; protein kinase C inhibitor 2; rotamase
Gene Symbols FKBP1A
Host Species Rabbit
Immunogen Recombinant Human FKBP1A protein (Met1-Glu108).
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2280
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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