FKBP1A Mouse anti-Human, Clone: OTI3B3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF500557

Catalog No. 50-165-9627

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

Specifications

• Antigen: FKBP1A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: FKBP1A
• Gene Alias: FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2280
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3B3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P62942
• Gene Symbols: FKBP1A
• Immunogen: Full length human recombit protein of human FKBP1A produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b