Invitrogen™ FKBP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115238

Catalog No. PIPA5115238

Description

Antibody detects endogenous levels of total FKBP25.

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

Specifications

• Antigen: FKBP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FKBP3
• Gene Alias: 25 kDa FK506-binding protein; 25 kDa FKBP; 25kDa; FK506 binding protein 3; FK506 binding protein 3, 25kDa; FK506-binding protein 25, T-cell; FK506-binding protein 3; FK506-binding protein 3 (25kD); FKBP25; FKBP-25; Fkbp3; FKBP-3; Immunophilin FKBP25; peptidyl-prolyl cis-trans isomerase FKBP3; PPIase; PPIase FKBP3; rapamycin binding protein; rapamycin-selective 25 kDa immunophilin; Rotamase
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2287, 299104, 30795
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q00688, Q62446
• Gene Symbols: FKBP3
• Immunogen: A synthesized peptide derived from human FKBP3(Accession Q00688), corresponding to amino acid residues E97-T147.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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