Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA545165

Invitrogen™ FKBP4 Monoclonal Antibody (Hi52C), PerCP
GREENER_CHOICE

Catalog No. PIMA545165
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA545165 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. PIMA545165 Supplier Invitrogen™ Supplier No. MA545165
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Mouse Monoclonal Antibody

0.5 μg/mL was sufficient for detection of FKBP52 in 20 μg total protein using WB by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary. Detects approximately 52kDa. Heavy chain migrates close to FKBP52 on SDS PAGE.

FKBP4, encoding FK506-binding protein 4, is part of the immunophilin family and plays roles in cellular processes like protein folding and trafficking. The FKBP4 gene is located on chromosome 12, where it encodes a protein involved in modulating the androgen receptor signaling pathway and has been implicated in various cancers, including non-small-cell lung cancer (NSCLC) and hepatocellular carcinoma (HCC). Structural variants of FKBP4 found through exome sequencing have shown potential deleterious effects on protein function. This gene is associated with cell proliferation, apoptosis, migration, and invasion in cancer cells. FKBP4 also influences metabolic processes, such as glycolysis, thereby contributing to cancer cell survival and growth. Importantly, FKBP4 has a role in disorders of sexual development due to its regulatory interaction with hormone signaling pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FKBP4
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone Hi52C
Concentration 1 mg/mL
Conjugate PerCP
Formulation 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative
Gene FKBP4
Gene Accession No. P30416, Q02790, Q9QVC8
Gene Alias 51 kDa FK506-binding protein; 52 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; 59kDa; AL022792; AW208983; FK506 binding protein 4; FK506 binding protein 4, 59kDa; FK506 binding protein 52; FK506-binding protein 4; FK506-binding protein 4 (59kD); FKBP prolyl isomerase 4; Fkbp4; FKBP-4; FKBP51; FKBP52; FKBP-52; FKBP52 protein; FKBP59; Fkpb52; HBI; HSP binding immunophilin; Hsp56; hsp90 binding protein; HSP-binding immunophilin; immunophilin FKBP52; p52; P59; p59 protein; peptidylprolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase FKBP4; Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed; PPIase; PPIase FKBP4; rotamase; T-cell FK506-binding protein, 59kD
Gene Symbols FKBP4
Host Species Mouse
Immunogen Synthetic peptide corresponding to the residues of human FKBP52.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100762395, 14228, 2288, 260321, 477726
Target Species Human, Mouse, Rat, Canine, Hamster
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2a
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.