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Invitrogen™ FKBP5 Monoclonal Antibody (Hi51B), FITC
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Catalog No. PIMA545161
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100 μg
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PIMA545161 100 μg
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Catalog No. PIMA545161 Supplier Invitrogen™ Supplier No. MA545161
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Description

Mouse Monoclonal Antibody

A 1:2,000 dilution was sufficient for detection of FKBP51 in approximately 50 μg total protein using WB analysis. Detects approximately 51kDa.

FKBP5 is a member of the immunophilin protein family. This family plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP5 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. The gene that encodes FKBP5 has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FKBP5
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone Hi51B
Concentration 1 mg/mL
Conjugate FITC
Formulation PBS, 9.09mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative
Gene FKBP5
Gene Accession No. Q13451, Q64378
Gene Alias 51 kDa FK506-binding protein; 51 kDa FKBP; 54 kDa progesterone receptor-associated immunophilin; AIG6; androgen-regulated protein 6; D17Ertd592e; Dit1; EC 5.2.1.8; FF1 antigen; FK506 binding protein 5; FK506-binding protein 5; FKBP prolyl isomerase 5; Fkbp5; FKBP-5; FKBP51; FKBP-51; FKBP54; HSP90-binding immunophilin; p54; peptidylprolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP5; PPIase; PPIase FKBP5; Ptg-10; rotamase; T-cell FK506-binding protein
Gene Symbols FKBP5
Host Species Mouse
Immunogen Synthetic peptide corresponding to the residues of human FKBP51.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100339155, 100760904, 14229, 2289, 361810, 481759
Target Species Human, Mouse, Rat, Canine, Rabbit, Hamster
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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