Invitrogen™ FLAP Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518283

Catalog No. PIPA518283

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Specifications

• Antigen: FLAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ALOX5AP
• Gene Alias: 5-lipoxygenase-activating protein FLAP; Alox5ap; arachidonate 5-lipoxygenase activating protein; arachidonate 5-lipoxygenase-activating protein; Flap; MK-886-binding protein
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 241
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P20292
• Gene Symbols: ALOX5AP
• Immunogen: Synthetic peptide sequence (KTISTTISPLLLIP) corresponding to the C-terminus amino acids of ALOX5AP (aa 148-161).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG