Invitrogen™ FLAP Recombinant Rabbit Monoclonal Antibody (2S7Z0)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537933

Catalog No. PIMA537933

Description

Positive Samples: A-549, THP-1, U-937 Immunogen sequence: DAYPTFLAVL WSAGLLCSQV PAAFAGLMYL FVRQKYFVGY LGERTQSTPG YIFGKRIILF LFLMSVAGIF NYYLIFFFGS DFENYIKTIS TTISPLLLIP.

ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Specifications

• Antigen: FLAP
• Classification: Recombinant Monoclonal
• Concentration: 0.58 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P20292
• Gene Symbols: ALOX5AP
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 62-161 of human FLAP (P20292).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 2S7Z0
• Conjugate: Unconjugated
• Gene: ALOX5AP
• Gene Alias: 5-lipoxygenase-activating protein FLAP; Alox5ap; arachidonate 5-lipoxygenase activating protein; arachidonate 5-lipoxygenase-activating protein; Flap; MK-886-binding protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 241
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid