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Invitrogen™ FLASH Polyclonal Antibody
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Catalog No. PA14167
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100 μg
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Catalog No. Quantity
PA14167 100 μg
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Catalog No. PA14167 Supplier Invitrogen™ Supplier No. PA14167
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Rabbit Polyclonal Antibody

PA1-4167 detects the FLASH protein in Human, rat, and mouse samples. PA1-4167 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~212 kDa protein representing FLASH in NIH3T3 cells. The PA1-4167 immunogen is a synthetic peptide corresponding to residues A(19) S P L K N N D E G S L D(31) of mouse FLASH. Maintain at 4ºC for 3 months or at -20ºC for longer periods. Stable for 1 year. Avoid repeated freeze/thaw cycles.

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FLASH
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CASP8AP2
Gene Accession No. Q9WUF3
Gene Alias AA387232; CASP8 associated protein 2; CASP8AP2; CASP8-associated protein 2; caspase 8 associated protein 2; CED-4; D4Ertd659e; FLASH; FLASH homolog RIP25; FLICE associated huge; FLICE-associated huge protein; FLJ11208; human FLASH; KIAA1315; mKIAA1315; RIP25; RP11-63K6.3
Gene Symbols CASP8AP2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues A(19) S P L K N N D E G S L D(31) of mouse FLASH.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26885
Target Species Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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