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Invitrogen™ FLI1 Polyclonal Antibody
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Catalog No. PIPA596374
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100 μL
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PIPA596374 100 μL
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Catalog No. PIPA596374 Supplier Invitrogen™ Supplier No. PA596374
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MDGTIKEALS VVSDDQSLFD SAYGAAAHLP KADMTASGSP DYGQPHKINP LPPQQEWINQ PVRVNVKREY DHMNGSRESP VDCSVSKCSK LVGGGESNPM; Positive Samples: THP-1, Jurkat, HepG2, Mouse heart; Cellular Location: Nucleus.

The FLI1 (Friend Leukemia Integration 1) gene is located on chromosome 11q24.3 and belongs to the ETS (E26 transformation-specific) family of transcription factors. Structurally, FLI1 contains an ETS domain responsible for DNA binding and a pointed domain which facilitates protein-protein interactions. Functionally, it plays a critical role in the regulation of embryonic and hematopoietic development. It is also implicated in the pathogenesis of diseases such as Ewing's sarcoma, wherein a chromosomal translocation t(11;22)(q24;q12) forms the EWS-FLI1 fusion gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FLI1
Applications ELISA, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.39 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Fli1
Gene Accession No. P26323, Q01543
Gene Alias Ewing sarcoma breakpoint region 2; EWSR2; Fli1; Fli-1; Fli-1 proto-oncogene, ETS transcription factor; Friend leukemia integration 1; Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; Proto-oncogene Fli-1; Retroviral integration site protein Fli-1; Sic1; SIC-1; transcription factor ERGB
Gene Symbols Fli1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human FLI1 (NP_0020082).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14247, 2313
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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